# get_proteome_by_id

Retrieve a proteome by UniProt Proteome ID.

Agent View of the PolicyLayer registry record for `get_proteome_by_id`. HTML page: https://policylayer.com/tools/gentel-lab-origenemcp/get-proteome-by-id

## Facts

- Tool: `get_proteome_by_id`
- Server: OrigeneMCP (`gentel-lab/origenemcp`) — https://policylayer.com/tools/gentel-lab-origenemcp.md
- Homepage: https://github.com/GENTEL-lab/OrigeneMCP
- Risk category: Read (Low risk)
- Registry record: grade C, identity unverified
- Server rate-limited: no
- Parameters: 0
- Recommended policy verdict: Allowed

## Example call (MCP tools/call, JSON-RPC 2.0)

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_proteome_by_id",
    "arguments": {}
  }
}
```

## Why get_proteome_by_id is rated Low

This is a straightforward data retrieval operation on a public biomedical database (UniProt). No execution, modification, or deletion occurs. The blast radius of misuse is minimal—an agent can only access proteome information already in the public domain. Severity is low because incorrect retrieval does not damage systems or data, and the read operation has no irreversible consequences.

From the tool's own definition: "Tool retrieves a proteome by UniProt Proteome ID. Uses verbs 'retrieve' and 'by ID', indicating read-only query without side effects. Returns existing data from a biomedical database without modification, creation, deletion, or execution."

## Use case

AI agents call get_proteome_by_id to retrieve information from OrigeneMCP without modifying anything. It is typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.

## Recommended policy (PolicyLayer)

Verdict: **Allowed**. Enforced by the PolicyLayer MCP gateway (https://policylayer.com/mcp-gateway) before a call reaches OrigeneMCP:

```json
{
  "version": "1",
  "default": "deny",
  "tools": {
    "get_proteome_by_id": {}
  }
}
```

## Other tools on OrigeneMCP (438)

- `post_vep_hgvs` — Execute — https://policylayer.com/tools/gentel-lab-origenemcp/post-vep-hgvs.md
- `post_vep_id` — Execute — https://policylayer.com/tools/gentel-lab-origenemcp/post-vep-id.md
- `post_ga4gh_features_search` — Other — https://policylayer.com/tools/gentel-lab-origenemcp/post-ga4gh-features-search.md
- `post_lookup_id` — Other — https://policylayer.com/tools/gentel-lab-origenemcp/post-lookup-id.md
- `check_genome_accessions` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/check-genome-accessions.md
- `check_virus_accessions` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/check-virus-accessions.md
- `clinvar_find_single_mutation` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/clinvar-find-single-mutation.md
- `clinvar_get_best_refseqid_by_sequence` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/clinvar-get-best-refseqid-by-sequence.md
- `clinvar_query_sequence_variants` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/clinvar-query-sequence-variants.md
- `clinvar_query_variant_significance` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/clinvar-query-variant-significance.md
- `depmap_comprehensive_analysis` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/depmap-comprehensive-analysis.md
- `depmap_get_dependency` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/depmap-get-dependency.md
- `depmap_get_expression` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/depmap-get-expression.md
- `depmap_get_mutation` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/depmap-get-mutation.md
- `ensembl_get_genes_by_band` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/ensembl-get-genes-by-band.md
- `get_activity` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-activity.md
- `get_activity_by_id` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-activity-by-id.md
- `get_activity_by_ids` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-activity-by-ids.md
- `get_activity_supplementary_data_by_activity` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-activity-supplementary-data-by-activity.md
- `get_activity_supplementary_data_by_activity_by_id` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-activity-supplementary-data-by-activity-by-id.md
- `get_activity_supplementary_data_by_activity_by_ids` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-activity-supplementary-data-by-activity-by-ids.md
- `get_alignment_region` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-alignment-region.md
- `get_all_interaction_partners_of_the_protein_set` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-all-interaction-partners-of-the-protein-set.md
- `get_archive_id` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-archive-id.md
- `get_assay` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-assay.md
- `get_assay_by_id` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-assay-by-id.md
- `get_assay_by_ids` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-assay-by-ids.md
- `get_assay_class` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-assay-class.md
- `get_assay_class_by_id` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-assay-class-by-id.md
- `get_assay_class_by_ids` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-assay-class-by-ids.md
- …and 408 more: https://policylayer.com/tools/gentel-lab-origenemcp.md

## For agents

This record is a snapshot. Live verdicts and the full registry:

- Check every server in your MCP config at once: `npx -y policylayer stack`
- Vet a server before you add it: install the mcp-precheck skill — `npx skills add https://policylayer.com` (skill text: https://policylayer.com/skill.md)
- Query the registry over MCP: endpoint `https://api.policylayer.com/mcp` — tools `check_mcp_server`, `check_mcp_stack`, `check_tool`, `search_registry`, `get_change_events`

---

Source: the PolicyLayer MCP registry — one continuously verified record per MCP server. Full record: https://policylayer.com/registry?q=gentel-lab-origenemcp · API: https://policylayer.com/registry/api · Policy library: https://policylayer.com/policies/gentel-lab-origenemcp