# stream_uniparc_cross_references_by_upi

A read tool on the OrigeneMCP MCP server.

Agent View of the PolicyLayer registry record for `stream_uniparc_cross_references_by_upi`. HTML page: https://policylayer.com/tools/gentel-lab-origenemcp/stream-uniparc-cross-references-by-upi

## Facts

- Tool: `stream_uniparc_cross_references_by_upi`
- Server: OrigeneMCP (`gentel-lab/origenemcp`) — https://policylayer.com/tools/gentel-lab-origenemcp.md
- Homepage: https://github.com/GENTEL-lab/OrigeneMCP
- Risk category: Read (Low risk)
- Registry record: grade C, identity unverified
- Server rate-limited: no
- Parameters: 0
- Recommended policy verdict: Allowed

## Example call (MCP tools/call, JSON-RPC 2.0)

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "stream_uniparc_cross_references_by_upi",
    "arguments": {}
  }
}
```

## Why stream_uniparc_cross_references_by_upi is rated Low

Based on the tool name alone, this appears to retrieve cross-reference data from UniParc protein database. The 'stream' prefix indicates iterative data retrieval rather than modification. With empty description and only the name as evidence, confidence is moderate. Classification defaults to Read as most likely, with low severity for read-only database queries which are inherently low-risk even if misused.

From the tool's own definition: "Tool name contains 'stream' and 'cross_references' indicating data retrieval/query operation. The 'by_upi' (UniParc Protein Index) parameter suggests lookup in biomedical database. No descriptions present to confirm write/execute/destructive operations."

## Use case

AI agents call stream_uniparc_cross_references_by_upi to retrieve information from OrigeneMCP without modifying anything. It is typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.

## Recommended policy (PolicyLayer)

Verdict: **Allowed**. Enforced by the PolicyLayer MCP gateway (https://policylayer.com/mcp-gateway) before a call reaches OrigeneMCP:

```json
{
  "version": "1",
  "default": "deny",
  "tools": {
    "stream_uniparc_cross_references_by_upi": {}
  }
}
```

## Other tools on OrigeneMCP (438)

- `post_vep_hgvs` — Execute — https://policylayer.com/tools/gentel-lab-origenemcp/post-vep-hgvs.md
- `post_vep_id` — Execute — https://policylayer.com/tools/gentel-lab-origenemcp/post-vep-id.md
- `post_ga4gh_features_search` — Other — https://policylayer.com/tools/gentel-lab-origenemcp/post-ga4gh-features-search.md
- `post_lookup_id` — Other — https://policylayer.com/tools/gentel-lab-origenemcp/post-lookup-id.md
- `check_genome_accessions` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/check-genome-accessions.md
- `check_virus_accessions` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/check-virus-accessions.md
- `clinvar_find_single_mutation` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/clinvar-find-single-mutation.md
- `clinvar_get_best_refseqid_by_sequence` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/clinvar-get-best-refseqid-by-sequence.md
- `clinvar_query_sequence_variants` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/clinvar-query-sequence-variants.md
- `clinvar_query_variant_significance` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/clinvar-query-variant-significance.md
- `depmap_comprehensive_analysis` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/depmap-comprehensive-analysis.md
- `depmap_get_dependency` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/depmap-get-dependency.md
- `depmap_get_expression` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/depmap-get-expression.md
- `depmap_get_mutation` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/depmap-get-mutation.md
- `ensembl_get_genes_by_band` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/ensembl-get-genes-by-band.md
- `get_activity` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-activity.md
- `get_activity_by_id` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-activity-by-id.md
- `get_activity_by_ids` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-activity-by-ids.md
- `get_activity_supplementary_data_by_activity` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-activity-supplementary-data-by-activity.md
- `get_activity_supplementary_data_by_activity_by_id` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-activity-supplementary-data-by-activity-by-id.md
- `get_activity_supplementary_data_by_activity_by_ids` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-activity-supplementary-data-by-activity-by-ids.md
- `get_alignment_region` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-alignment-region.md
- `get_all_interaction_partners_of_the_protein_set` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-all-interaction-partners-of-the-protein-set.md
- `get_archive_id` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-archive-id.md
- `get_assay` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-assay.md
- `get_assay_by_id` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-assay-by-id.md
- `get_assay_by_ids` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-assay-by-ids.md
- `get_assay_class` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-assay-class.md
- `get_assay_class_by_id` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-assay-class-by-id.md
- `get_assay_class_by_ids` — Read — https://policylayer.com/tools/gentel-lab-origenemcp/get-assay-class-by-ids.md
- …and 408 more: https://policylayer.com/tools/gentel-lab-origenemcp.md

## For agents

This record is a snapshot. Live verdicts and the full registry:

- Check every server in your MCP config at once: `npx -y policylayer stack`
- Vet a server before you add it: install the mcp-precheck skill — `npx skills add https://policylayer.com` (skill text: https://policylayer.com/skill.md)
- Query the registry over MCP: endpoint `https://api.policylayer.com/mcp` — tools `check_mcp_server`, `check_mcp_stack`, `check_tool`, `search_registry`, `get_change_events`

---

Source: the PolicyLayer MCP registry — one continuously verified record per MCP server. Full record: https://policylayer.com/registry?q=gentel-lab-origenemcp · API: https://policylayer.com/registry/api · Policy library: https://policylayer.com/policies/gentel-lab-origenemcp