# mygene.genes.search

Search the MyGene.info gene database by keyword, gene symbol, gene name, GO term, or any other gene annotation. Backed by NCBI Entrez Gene, Ensembl, UniProt, and other authoritative databases aggregated by the BioThings project. Returns NCBI Gene IDs, symbols, names, gene type, taxon, and summary text. Supports wildcard queries (e.g. "CDK*" returns all CDK family members) and species filtering. Use the returned Entrez Gene IDs with mygene.genes.info or mygene.genes.batch for full annotations including GO terms, KEGG/Reactome pathways, UniProt accessions, and genomic coordinates.

Agent View of the PolicyLayer registry record for `mygene.genes.search`. HTML page: https://policylayer.com/tools/io-github-whiteknightonhorse-apibase/mygene.genes.search

## Facts

- Tool: `mygene.genes.search`
- Server: Apibase (`apibase-mcp-client`) — https://policylayer.com/tools/io-github-whiteknightonhorse-apibase.md
- Install: `npx -y apibase-mcp-client`
- Homepage: https://github.com/whiteknightonhorse/APIbase
- Risk category: Read (Low risk)
- Registry record: grade F, identity unverified
- Server auth posture: open
- Server rate-limited: no
- Parameters: 4 (1 required)
- Recommended policy verdict: Allowed

## Parameters

| Parameter | Type | Required | Description |
| --- | --- | --- | --- |
| `q` | string | yes | Gene query string. Supports full-text search by gene symbol (e.g. "BRCA1"), gene name (e.g. "breast cancer 1"), keyword (e.g. "kinase"), GO term ID (e.g. "GO:00 |
| `size` | integer | no | Maximum number of gene results to return (1–50, default 10). |
| `fields` | string | no | Comma-separated fields to return per hit. Default: symbol,name,taxid,entrezgene,type_of_gene,summary. Other useful fields: ensembl.gene, uniprot, alias, genomic |
| `species` | string | no | Filter by species. Common values: "human" (Homo sapiens, taxid 9606), "mouse" (Mus musculus, taxid 10090), "rat" (Rattus norvegicus), "fruitfly" (Drosophila mel |

Parameters from the server's own tool schema.

## Example call (MCP tools/call, JSON-RPC 2.0)

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "mygene.genes.search",
    "arguments": {
      "q": "<q>"
    }
  }
}
```

## Why mygene.genes.search is rated Low

Tool retrieves gene information without modifying data or triggering external operations.

From the tool's own definition: "Search gene database by keyword, returns gene IDs and annotations; read-only query."

## Use case

AI agents call mygene.genes.search to retrieve information from Apibase without modifying anything. It is typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.

## Recommended policy (PolicyLayer)

Verdict: **Allowed**. Enforced by the PolicyLayer MCP gateway (https://policylayer.com/mcp-gateway) before a call reaches Apibase:

```json
{
  "version": "1",
  "default": "deny",
  "tools": {
    "mygene.genes.search": {}
  }
}
```

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## For agents

This record is a snapshot. Live verdicts and the full registry:

- Check every server in your MCP config at once: `npx -y policylayer stack`
- Vet a server before you add it: install the mcp-precheck skill — `npx skills add https://policylayer.com` (skill text: https://policylayer.com/skill.md)
- Query the registry over MCP: endpoint `https://api.policylayer.com/mcp` — tools `check_mcp_server`, `check_mcp_stack`, `check_tool`, `search_registry`, `get_change_events`

---

Source: the PolicyLayer MCP registry — one continuously verified record per MCP server. Full record: https://policylayer.com/registry?q=io-github-whiteknightonhorse-apibase · API: https://policylayer.com/registry/api · Policy library: https://policylayer.com/policies/io-github-whiteknightonhorse-apibase