# myvariant.variants.batch

Retrieve annotations for up to 1000 genetic variants in a single request by providing a comma-separated list of dbSNP rsIDs or HGVS variant IDs. Returns ClinVar significance, CADD scores, gnomAD allele frequencies, and functional consequence predictions for each variant in one call. Ideal for annotating VCF files, enriching GWAS hit lists, building polygenic risk score pipelines, or bulk pharmacogenomics analysis. Variants not found in the database are marked with found=false. Mix rsIDs from different chromosomes freely — no grouping by position required.

Agent View of the PolicyLayer registry record for `myvariant.variants.batch`. HTML page: https://policylayer.com/tools/io-github-whiteknightonhorse-apibase/myvariant.variants.batch

## Facts

- Tool: `myvariant.variants.batch`
- Server: Apibase (`apibase-mcp-client`) — https://policylayer.com/tools/io-github-whiteknightonhorse-apibase.md
- Install: `npx -y apibase-mcp-client`
- Homepage: https://github.com/whiteknightonhorse/APIbase
- Risk category: Read (Low risk)
- Registry record: grade F, identity unverified
- Server auth posture: open
- Server rate-limited: no
- Parameters: 2 (1 required)
- Recommended policy verdict: Allowed

## Parameters

| Parameter | Type | Required | Description |
| --- | --- | --- | --- |
| `ids` | string | yes | Comma-separated list of variant identifiers to retrieve in a single request. Accepts dbSNP rsIDs (e.g. "rs58991260,rs671,rs1801133") or HGVS genomic IDs. Mix of |
| `fields` | string | no | Comma-separated annotation fields to return for each variant. Default: dbsnp,clinvar,cadd,gnomad_exome,gnomad_genome,snpeff,vcf,chrom,hg19. Limit fields for lar |

Parameters from the server's own tool schema.

## Example call (MCP tools/call, JSON-RPC 2.0)

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "myvariant.variants.batch",
    "arguments": {
      "ids": "<ids>"
    }
  }
}
```

## Why myvariant.variants.batch is rated Low

Retrieves and queries genetic variant annotations without modifying data or triggering external operations.

From the tool's own definition: "Retrieve annotations for genetic variants, Returns ClinVar significance, CADD scores, gnomAD allele frequencies"

## Use case

AI agents call myvariant.variants.batch to retrieve information from Apibase without modifying anything. It is typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.

## Recommended policy (PolicyLayer)

Verdict: **Allowed**. Enforced by the PolicyLayer MCP gateway (https://policylayer.com/mcp-gateway) before a call reaches Apibase:

```json
{
  "version": "1",
  "default": "deny",
  "tools": {
    "myvariant.variants.batch": {}
  }
}
```

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## For agents

This record is a snapshot. Live verdicts and the full registry:

- Check every server in your MCP config at once: `npx -y policylayer stack`
- Vet a server before you add it: install the mcp-precheck skill — `npx skills add https://policylayer.com` (skill text: https://policylayer.com/skill.md)
- Query the registry over MCP: endpoint `https://api.policylayer.com/mcp` — tools `check_mcp_server`, `check_mcp_stack`, `check_tool`, `search_registry`, `get_change_events`

---

Source: the PolicyLayer MCP registry — one continuously verified record per MCP server. Full record: https://policylayer.com/registry?q=io-github-whiteknightonhorse-apibase · API: https://policylayer.com/registry/api · Policy library: https://policylayer.com/policies/io-github-whiteknightonhorse-apibase