clinvar_find_single_mutation
A read tool on the Origene MCP server.
This record as markdown: /tools/gentel-lab-origenemcp/clinvar-find-single-mutation.md
What clinvar_find_single_mutation does on OrigeneMCP
AI agents call clinvar_find_single_mutation to retrieve information from OrigeneMCP without modifying anything. It is typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.
Why clinvar_find_single_mutation is rated Low
ClinVar is a public database of genetic variants and their clinical significance. A 'find' operation on such a database is a retrieval/query action with no side effects or ability to modify data. This is a Read category tool. Confidence is moderate (0.75) rather than high due to empty description, but the naming pattern and sibling context strongly suggest read-only database lookup.
From the tool's definition Tool name 'clinvar_find_single_mutation' suggests querying ClinVar database for mutation information. No description provided, but context from sibling tools (clinvar_query_sequence_variants, clinvar_query_variant_significance) indicates this server provides…
Attacks that exploit this kind of access
The rule that runs clinvar_find_single_mutation safely
PolicyLayer is an MCP gateway: it sits between your AI agents and OrigeneMCP, and checks every tool call against a rule you set before the call runs. Nothing changes on the server itself. For clinvar_find_single_mutation, this is the rule to start with:
clinvar_find_single_mutation is read-only, so it stays allowed. Everything else on the server is denied unless you say otherwise.
The button opens the PolicyLayer dashboard: create your workspace, connect OrigeneMCP, apply this rule, and every clinvar_find_single_mutation call is checked against it from then on.
Questions about clinvar_find_single_mutation
clinvar_find_single_mutation is a read tool on the Origene MCP server. It is categorised as a Read tool in the OrigeneMCP MCP Server, which means it retrieves data without modifying state.
Register the Origene MCP server in PolicyLayer and add a rule for clinvar_find_single_mutation: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches OrigeneMCP. Nothing to install.
clinvar_find_single_mutation is a Read tool with low risk. Read-only tools are generally safe to allow by default.
Yes. Add a rate_limit block to the clinvar_find_single_mutation rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.
Set action: deny in the PolicyLayer policy for clinvar_find_single_mutation. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.
clinvar_find_single_mutation is provided by the Origene MCP server (gentel-lab/origenemcp). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.
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