clinvar_query_sequence_variants

A read tool on the Origene MCP server.

SERVEROrigeneMCP SOURCEgentel-lab/origenemcp

Low RISK CLASS

Category Read

Parameters 00 required

Recommended Allowedsee the rule below

Registry record Grade C, identity unverified Pull the record →

This record as markdown: /tools/gentel-lab-origenemcp/clinvar-query-sequence-variants.md

WHAT IT DOES

What clinvar_query_sequence_variants does on OrigeneMCP

AI agents call clinvar_query_sequence_variants to retrieve information from OrigeneMCP without modifying anything. It is typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.

RISK

Why clinvar_query_sequence_variants is rated Low

The naming pattern and context from sibling tools strongly suggest this retrieves variant information from ClinVar without modification. ClinVar is a public reference database for clinical significance of human variants. 'Query' is a read operation with no documented side effects.

From the tool's definition Tool name 'clinvar_query_sequence_variants' indicates querying (a read operation) against ClinVar, a public biomedical database.

Attacks that exploit this kind of access

RECOMMENDED RULE

The rule that runs clinvar_query_sequence_variants safely

PolicyLayer is an MCP gateway: it sits between your AI agents and OrigeneMCP, and checks every tool call against a rule you set before the call runs. Nothing changes on the server itself. For clinvar_query_sequence_variants, this is the rule to start with:

clinvar_query_sequence_variants Allowed

clinvar_query_sequence_variants is read-only, so it stays allowed. Everything else on the server is denied unless you say otherwise.

View as policy code

policy.json

{
  "version": "1",
  "default": "deny",
  "tools": {
    "clinvar_query_sequence_variants": {}
  }
}

ALLOW ONLY THIS TOOL → Instant setup, no code required.

The button opens the PolicyLayer dashboard: create your workspace, connect OrigeneMCP, apply this rule, and every clinvar_query_sequence_variants call is checked against it from then on.

FAQ

Questions about clinvar_query_sequence_variants

What does the clinvar_query_sequence_variants tool do? +

clinvar_query_sequence_variants is a read tool on the Origene MCP server. It is categorised as a Read tool in the OrigeneMCP MCP Server, which means it retrieves data without modifying state.

How do I enforce a policy on clinvar_query_sequence_variants? +

Register the Origene MCP server in PolicyLayer and add a rule for clinvar_query_sequence_variants: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches OrigeneMCP. Nothing to install.

What risk level is clinvar_query_sequence_variants? +

clinvar_query_sequence_variants is a Read tool with low risk. Read-only tools are generally safe to allow by default.

Can I rate-limit clinvar_query_sequence_variants? +

Yes. Add a rate_limit block to the clinvar_query_sequence_variants rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.

How do I block clinvar_query_sequence_variants completely? +

Set action: deny in the PolicyLayer policy for clinvar_query_sequence_variants. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.

What MCP server provides clinvar_query_sequence_variants? +

clinvar_query_sequence_variants is provided by the Origene MCP server (gentel-lab/origenemcp). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.

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