AI agents call search_uniprotkb_entries to retrieve information from OrigeneMCP without modifying anything — typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.
The tool queries UniProtKB, a public protein database, to retrieve information about protein entries. No modification, deletion, code execution, or financial transaction occurs. This is a read operation with no side effects. Severity is low because it only accesses public reference data without operational risk.
From the tool's definition Tool name is 'search_uniprotkb_entries'; the verb 'search' indicates a read-only retrieval operation. UniProtKB is a protein sequence database, and searching it would retrieve/query data.
Documented attack patterns abuse exactly the kind of access search_uniprotkb_entries gives an agent:
PolicyLayer is an MCP gateway — it sits between your AI agents and OrigeneMCP, and nothing reaches the server without passing your rules. This is the rule we recommend for search_uniprotkb_entries:
{
"version": "1",
"default": "deny",
"tools": {
"search_uniprotkb_entries": {}
}
}search_uniprotkb_entries is read-only, so it stays allowed — but everything else on the server is denied unless you say otherwise.
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search_uniprotkb_entries. It is categorised as a Read tool in the OrigeneMCP MCP Server, which means it retrieves data without modifying state.
Register the Origene MCP server in PolicyLayer and add a rule for search_uniprotkb_entries: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches OrigeneMCP. Nothing to install.
search_uniprotkb_entries is a Read tool with low risk. Read-only tools are generally safe to allow by default.
Yes. Add a rate_limit block to the search_uniprotkb_entries rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.
Set action: deny in the PolicyLayer policy for search_uniprotkb_entries. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.
search_uniprotkb_entries is provided by the Origene MCP server (gentel-lab/origenemcp). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.
Start from OrigeneMCP, add the rest of your stack, and see everything your agents can call. Then put policy on all of it.
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439 OrigeneMCP tools catalogued and risk-classified — across an index of 43,000+ MCP servers.