Low Risk

depmap_get_mutation

depmap_get_mutation

How to control depmap_get_mutation ↓

What depmap_get_mutation does on OrigeneMCP

AI agents call depmap_get_mutation to retrieve information from OrigeneMCP without modifying anything — typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.

Low Risk

Why depmap_get_mutation needs a policy

Although the description is empty, the tool name and context strongly indicate this is a query/retrieval function operating on biomedical databases. The 'get_' prefix and sibling tools using similar patterns suggest no side effects or data modification.

From the tool's definition Tool name 'depmap_get_mutation' suggests retrieval of mutation data from the DepMap (Cancer Dependency Map) database.

Documented attack patterns abuse exactly the kind of access depmap_get_mutation gives an agent:

How to control depmap_get_mutation

PolicyLayer is an MCP gateway — it sits between your AI agents and OrigeneMCP, and nothing reaches the server without passing your rules. This is the rule we recommend for depmap_get_mutation:

policy.json
{
  "version": "1",
  "default": "deny",
  "tools": {
    "depmap_get_mutation": {}
  }
}

depmap_get_mutation is read-only, so it stays allowed — but everything else on the server is denied unless you say otherwise.

  1. Create a free account and register OrigeneMCP — nothing to install.
  2. Add this policy — paste it, or build it visually.
  3. Point your MCP client (Claude, Cursor, anything) at your gateway URL.
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Related tools and policies

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Questions about depmap_get_mutation

What does the depmap_get_mutation tool do? +

depmap_get_mutation. It is categorised as a Read tool in the OrigeneMCP MCP Server, which means it retrieves data without modifying state.

How do I enforce a policy on depmap_get_mutation? +

Register the Origene MCP server in PolicyLayer and add a rule for depmap_get_mutation: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches OrigeneMCP. Nothing to install.

What risk level is depmap_get_mutation? +

depmap_get_mutation is a Read tool with low risk. Read-only tools are generally safe to allow by default.

Can I rate-limit depmap_get_mutation? +

Yes. Add a rate_limit block to the depmap_get_mutation rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.

How do I block depmap_get_mutation completely? +

Set action: deny in the PolicyLayer policy for depmap_get_mutation. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.

What MCP server provides depmap_get_mutation? +

depmap_get_mutation is provided by the Origene MCP server (gentel-lab/origenemcp). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.

Enforce policy on every OrigeneMCP tool call.

Start from OrigeneMCP, add the rest of your stack, and see everything your agents can call. Then put policy on all of it.

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