AI agents call get_disease_efo_id to retrieve information from OrigeneMCP without modifying anything — typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.
This is a straightforward data retrieval tool with no side effects. It performs a read-only query operation to map a disease name to its standardized ontology identifier. There is no data modification, code execution, deletion, or financial impact. The low severity reflects minimal risk even if an AI agent misuses it—worst case it returns incorrect or no results.
From the tool's definition Tool name 'get_disease_efo_id' and description 'Get disease EFO ID by disease name' indicate a lookup/retrieval operation that queries a biomedical database (EFO - Experimental Factor Ontology) to retrieve an identifier based on disease name input.
Documented attack patterns abuse exactly the kind of access get_disease_efo_id gives an agent:
PolicyLayer is an MCP gateway — it sits between your AI agents and OrigeneMCP, and nothing reaches the server without passing your rules. This is the rule we recommend for get_disease_efo_id:
{
"version": "1",
"default": "deny",
"tools": {
"get_disease_efo_id": {}
}
}get_disease_efo_id is read-only, so it stays allowed — but everything else on the server is denied unless you say otherwise.
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Get disease EFO ID by disease name. It is categorised as a Read tool in the OrigeneMCP MCP Server, which means it retrieves data without modifying state.
Register the Origene MCP server in PolicyLayer and add a rule for get_disease_efo_id: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches OrigeneMCP. Nothing to install.
get_disease_efo_id is a Read tool with low risk. Read-only tools are generally safe to allow by default.
Yes. Add a rate_limit block to the get_disease_efo_id rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.
Set action: deny in the PolicyLayer policy for get_disease_efo_id. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.
get_disease_efo_id is provided by the Origene MCP server (gentel-lab/origenemcp). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.
Start from OrigeneMCP, add the rest of your stack, and see everything your agents can call. Then put policy on all of it.
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