Low Risk

get_ga4gh_variantsets

Return the GA4GH record for a specific VariantSet given its identifier

How to control get_ga4gh_variantsets ↓

What get_ga4gh_variantsets does on OrigeneMCP

AI agents call get_ga4gh_variantsets to retrieve information from OrigeneMCP without modifying anything — typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.

Low Risk

Why get_ga4gh_variantsets needs a policy

This tool fetches and returns existing genomic variant set metadata from a GA4GH-compliant database. It has no capability to modify data, execute commands, delete records, or perform financial transactions. The blast radius of misuse is minimal—an attacker could only retrieve publicly available or authorized genomic reference data. The tool is purely informational.

From the tool's definition Tool description states 'Return the GA4GH record for a specific VariantSet given its identifier' — a retrieval operation with no modification, deletion, or execution of arbitrary code.

Documented attack patterns abuse exactly the kind of access get_ga4gh_variantsets gives an agent:

How to control get_ga4gh_variantsets

PolicyLayer is an MCP gateway — it sits between your AI agents and OrigeneMCP, and nothing reaches the server without passing your rules. This is the rule we recommend for get_ga4gh_variantsets:

policy.json
{
  "version": "1",
  "default": "deny",
  "tools": {
    "get_ga4gh_variantsets": {}
  }
}

get_ga4gh_variantsets is read-only, so it stays allowed — but everything else on the server is denied unless you say otherwise.

  1. Create a free account and register OrigeneMCP — nothing to install.
  2. Add this policy — paste it, or build it visually.
  3. Point your MCP client (Claude, Cursor, anything) at your gateway URL.
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Related tools and policies

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Questions about get_ga4gh_variantsets

What does the get_ga4gh_variantsets tool do? +

Return the GA4GH record for a specific VariantSet given its identifier. It is categorised as a Read tool in the OrigeneMCP MCP Server, which means it retrieves data without modifying state.

How do I enforce a policy on get_ga4gh_variantsets? +

Register the Origene MCP server in PolicyLayer and add a rule for get_ga4gh_variantsets: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches OrigeneMCP. Nothing to install.

What risk level is get_ga4gh_variantsets? +

get_ga4gh_variantsets is a Read tool with low risk. Read-only tools are generally safe to allow by default.

Can I rate-limit get_ga4gh_variantsets? +

Yes. Add a rate_limit block to the get_ga4gh_variantsets rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.

How do I block get_ga4gh_variantsets completely? +

Set action: deny in the PolicyLayer policy for get_ga4gh_variantsets. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.

What MCP server provides get_ga4gh_variantsets? +

get_ga4gh_variantsets is provided by the Origene MCP server (gentel-lab/origenemcp). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.

Enforce policy on every OrigeneMCP tool call.

Start from OrigeneMCP, add the rest of your stack, and see everything your agents can call. Then put policy on all of it.

Free to start. No card required.

439 OrigeneMCP tools catalogued and risk-classified — across an index of 43,000+ MCP servers.

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