AI agents call get_tissue_ids to retrieve information from OrigeneMCP without modifying anything — typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.
This is a straightforward data retrieval tool that fetches tissue information from a biomedical database. It performs a read-only query operation with no capacity to modify, delete, or execute arbitrary operations. The blast radius of misuse is minimal—at worst, an agent could retrieve tissue metadata it shouldn't access, but this would be an access control issue rather than a tool capability issue.
From the tool's definition Tool name 'get_tissue_ids' and description 'Retrieve single tissue object details by IDs' indicate a query/retrieval operation with no side effects. No modification, deletion, execution, or financial operation is described.
Documented attack patterns abuse exactly the kind of access get_tissue_ids gives an agent:
PolicyLayer is an MCP gateway — it sits between your AI agents and OrigeneMCP, and nothing reaches the server without passing your rules. This is the rule we recommend for get_tissue_ids:
{
"version": "1",
"default": "deny",
"tools": {
"get_tissue_ids": {}
}
}get_tissue_ids is read-only, so it stays allowed — but everything else on the server is denied unless you say otherwise.
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Retrieve single tissue object details by IDs. It is categorised as a Read tool in the OrigeneMCP MCP Server, which means it retrieves data without modifying state.
Register the Origene MCP server in PolicyLayer and add a rule for get_tissue_ids: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches OrigeneMCP. Nothing to install.
get_tissue_ids is a Read tool with low risk. Read-only tools are generally safe to allow by default.
Yes. Add a rate_limit block to the get_tissue_ids rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.
Set action: deny in the PolicyLayer policy for get_tissue_ids. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.
get_tissue_ids is provided by the Origene MCP server (gentel-lab/origenemcp). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.
Start from OrigeneMCP, add the rest of your stack, and see everything your agents can call. Then put policy on all of it.
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