AI agents call get_proteome_by_id to retrieve information from OrigeneMCP without modifying anything — typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.
This is a straightforward data retrieval operation on a public biomedical database (UniProt). No execution, modification, or deletion occurs. The blast radius of misuse is minimal—an agent can only access proteome information already in the public domain. Severity is low because incorrect retrieval does not damage systems or data, and the read operation has no irreversible consequences.
From the tool's definition Tool retrieves a proteome by UniProt Proteome ID. Uses verbs 'retrieve' and 'by ID', indicating read-only query without side effects. Returns existing data from a biomedical database without modification, creation, deletion, or execution.
Documented attack patterns abuse exactly the kind of access get_proteome_by_id gives an agent:
PolicyLayer is an MCP gateway — it sits between your AI agents and OrigeneMCP, and nothing reaches the server without passing your rules. This is the rule we recommend for get_proteome_by_id:
{
"version": "1",
"default": "deny",
"tools": {
"get_proteome_by_id": {}
}
}get_proteome_by_id is read-only, so it stays allowed — but everything else on the server is denied unless you say otherwise.
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Retrieve a proteome by UniProt Proteome ID. It is categorised as a Read tool in the OrigeneMCP MCP Server, which means it retrieves data without modifying state.
Register the Origene MCP server in PolicyLayer and add a rule for get_proteome_by_id: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches OrigeneMCP. Nothing to install.
get_proteome_by_id is a Read tool with low risk. Read-only tools are generally safe to allow by default.
Yes. Add a rate_limit block to the get_proteome_by_id rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.
Set action: deny in the PolicyLayer policy for get_proteome_by_id. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.
get_proteome_by_id is provided by the Origene MCP server (gentel-lab/origenemcp). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.
Start from OrigeneMCP, add the rest of your stack, and see everything your agents can call. Then put policy on all of it.
Free to start. No card required.
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