High-risk tools in Gwas
5 of the 44 tools in Gwas are classified as high risk. This page profiles those tools specifically, with recommended policy actions and the attack patterns that target them.
Every operation listed below is an action PolicyLayer recommends controlling at the transport layer. Open any tool to see the full profile, risk score, and YAML policy snippet.
Tools at high risk
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calculate_heritability_ldscExecuteEstimate SNP-heritability using LD Score regression. Requires GWAS summary statistics and LD scores.
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calculate_pcaExecutePerform Principal Component Analysis for population stratification. Uses PLINK files as input.
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clump_snpsExecutePerform LD-based clumping of GWAS results to identify independent significant signals.
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ld_pruningExecutePrune SNPs based on linkage disequilibrium (LD). Removes variants in high LD to create an independent set.
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run_gwasExecutePerform genome-wide association study using linear or logistic regression. Returns summary statistics including p-values, beta coefficients, and standard errors.
Attacks that target this class
High-risk tools in any server share these documented attack patterns. Each links to the full case and the defensive policy.