chembl.activity.bioactivity
Retrieve bioactivity data (potency measurements) for a drug molecule or biological target from ChEMBL's curated assay database. Returns activity type (IC50, Ki, EC50, Kd, MIC, GI50), measured value and units, relation operator (<, =, >), pChEMBL value (−log10 molar, comparable across assay types)...
This record as markdown: /tools/io-github-whiteknightonhorse-apibase/chembl.activity.bioactivity.md
What chembl.activity.bioactivity does on Apibase
AI agents call chembl.activity.bioactivity to retrieve information from Apibase without modifying anything. It is typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.
| Parameter | Type | Required | Description |
|---|---|---|---|
limit | integer | — | Number of activity records to return (1–25, default 10). |
activity_type | string | — | Filter by activity measurement type. Common values: IC50 (inhibitor concentration 50%), Ki (inhibition constant), EC50 (effective concentration 50%), Kd (dissoc |
target_chembl_id | string | — | ChEMBL target ID to retrieve bioactivity data for (e.g. CHEMBL220 for Acetylcholinesterase). Returns activity measurements from all tested compounds against thi |
molecule_chembl_id | string | — | ChEMBL molecule ID to retrieve bioactivity data for (e.g. CHEMBL25). Returns all assay measurements for this compound. Provide at least one of molecule_chembl_i |
Parameters from the server's own tool schema.
Why chembl.activity.bioactivity is rated Low
Tool retrieves and queries existing bioactivity data without modifying or executing operations.
From the tool's definition Retrieve bioactivity data, curated assay database, returns activity measurements.
Attacks that exploit this kind of access
The rule that runs chembl.activity.bioactivity safely
PolicyLayer is an MCP gateway: it sits between your AI agents and Apibase, and checks every tool call against a rule you set before the call runs. Nothing changes on the server itself. For chembl.activity.bioactivity, this is the rule to start with:
chembl.activity.bioactivity is read-only, so it stays allowed. Everything else on the server is denied unless you say otherwise.
The button opens the PolicyLayer dashboard: create your workspace, connect Apibase, apply this rule, and every chembl.activity.bioactivity call is checked against it from then on.
Questions about chembl.activity.bioactivity
Retrieve bioactivity data (potency measurements) for a drug molecule or biological target from ChEMBL's curated assay database. Returns activity type (IC50, Ki, EC50, Kd, MIC, GI50), measured value and units, relation operator (<, =, >), pChEMBL value (−log10 molar, comparable across assay types), assay ChEMBL ID, assay description, and source document ChEMBL ID. Filter by activity_type (e.g. "IC50") to focus on one measurement class. Requires at least one of: molecule_chembl_id (compound-centric) or target_chembl_id (target-centric, all inhibitors). ChEMBL contains 20M+ curated bioactivity measurements from scientific literature. Source: EMBL-EBI ChEMBL — CC BY-SA 3.0, no auth required. It is categorised as a Read tool in the Apibase MCP Server, which means it retrieves data without modifying state.
chembl.activity.bioactivity accepts 4 parameters: limit, activity_type, target_chembl_id, molecule_chembl_id. The full parameter table on this page comes from the server's own tool schema.
Register the Apibase MCP server in PolicyLayer and add a rule for chembl.activity.bioactivity: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches Apibase. Nothing to install.
chembl.activity.bioactivity is a Read tool with low risk. Read-only tools are generally safe to allow by default.
Yes. Add a rate_limit block to the chembl.activity.bioactivity rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.
Set action: deny in the PolicyLayer policy for chembl.activity.bioactivity. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.
chembl.activity.bioactivity is provided by the Apibase MCP server (apibase-mcp-client). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.
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