myvariant.variants.search
Search the MyVariant.info database of 450M+ annotated human genetic variants using a flexible query syntax. Query by: dbSNP rsID (e.g. "rs58991260"), gene symbol (e.g. "dbsnp.gene.symbol:BRCA1"), ClinVar clinical significance (e.g. "clinvar.rcv.clinical_significance:Pathogenic"), CADD pathogenici...
This record as markdown: /tools/io-github-whiteknightonhorse-apibase/myvariant.variants.search.md
What myvariant.variants.search does on Apibase
AI agents call myvariant.variants.search to retrieve information from Apibase without modifying anything. It is typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.
| Parameter | Type | Required | Description |
|---|---|---|---|
q | string | Yes | Variant query string. Supports: rsID (e.g. "rs58991260"), gene symbol (e.g. "dbsnp.gene.symbol:BRCA1"), CADD score filter (e.g. "cadd.phred:>20"), ClinVar signi |
size | integer | — | Maximum number of variant results to return (1–50, default 10). |
fields | string | — | Comma-separated fields to return per hit. Default: dbsnp,clinvar,cadd,gnomad_exome,gnomad_genome,snpeff,vcf,chrom,hg19. Other useful fields: dbnsfp,cosmic,civic |
assembly | string | — | Genome assembly for coordinate fields in results. "hg19" (GRCh37) or "hg38" (GRCh38). Defaults to hg19. |
Parameters from the server's own tool schema.
Why myvariant.variants.search is rated Low
Tool only queries and retrieves genetic variant data with no side effects.
From the tool's definition Search the MyVariant.info database... annotated human genetic variants
Attacks that exploit this kind of access
The rule that runs myvariant.variants.search safely
PolicyLayer is an MCP gateway: it sits between your AI agents and Apibase, and checks every tool call against a rule you set before the call runs. Nothing changes on the server itself. For myvariant.variants.search, this is the rule to start with:
myvariant.variants.search is read-only, so it stays allowed. Everything else on the server is denied unless you say otherwise.
The button opens the PolicyLayer dashboard: create your workspace, connect Apibase, apply this rule, and every myvariant.variants.search call is checked against it from then on.
Questions about myvariant.variants.search
Search the MyVariant.info database of 450M+ annotated human genetic variants using a flexible query syntax. Query by: dbSNP rsID (e.g. "rs58991260"), gene symbol (e.g. "dbsnp.gene.symbol:BRCA1"), ClinVar clinical significance (e.g. "clinvar.rcv.clinical_significance:Pathogenic"), CADD pathogenicity score (e.g. "cadd.phred:>30"), chromosomal position range (e.g. "chrom:17 AND hg19.start:[41196312 TO 41277500]"), or disease/phenotype keywords (e.g. "clinvar.rcv.conditions.name:breast cancer"). Each hit includes chromosome, genomic position (hg19/hg38), rsID, reference/alternate alleles, CADD PHRED score, ClinVar clinical significance, gnomAD allele frequency, and predicted functional consequences (SnpEff). Data integrates ClinVar, gnomAD, CADD, dbSNP, COSMIC, CIViC, ExAC, and 30+ annotation sources. It is categorised as a Read tool in the Apibase MCP Server, which means it retrieves data without modifying state.
myvariant.variants.search accepts 4 parameters: q, size, fields, assembly. Required: q. The full parameter table on this page comes from the server's own tool schema.
Register the Apibase MCP server in PolicyLayer and add a rule for myvariant.variants.search: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches Apibase. Nothing to install.
myvariant.variants.search is a Read tool with low risk. Read-only tools are generally safe to allow by default.
Yes. Add a rate_limit block to the myvariant.variants.search rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.
Set action: deny in the PolicyLayer policy for myvariant.variants.search. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.
myvariant.variants.search is provided by the Apibase MCP server (apibase-mcp-client). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.
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