pharmgkb.pharmacology.gene_search
Search PharmGKB for a pharmacogenomics gene by HGNC symbol (e.g. CYP2C9, CYP2D6, BRCA1, VKORC1, TPMT). Returns the PharmGKB gene ID, chromosomal location (GRCh38), strand, CPIC/AMP gene status, allele type, VIP tier, and plain-text clinical summary. CPIC genes have validated drug-dosing guideline...
This record as markdown: /tools/io-github-whiteknightonhorse-apibase/pharmgkb.pharmacology.gene-search.md
What pharmgkb.pharmacology.gene_search does on Apibase
AI agents call pharmgkb.pharmacology.gene_search to retrieve information from Apibase without modifying anything. It is typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.
| Parameter | Type | Required | Description |
|---|---|---|---|
symbol | string | Yes | HGNC gene symbol to search for (e.g. CYP2C9, CYP2D6, BRCA1, VKORC1, TPMT). Case-insensitive. Use the official gene symbol as listed by HGNC. |
Parameters from the server's own tool schema.
Why pharmgkb.pharmacology.gene_search is rated Low
Retrieves pharmacogenomics data from PharmGKB without modifying or executing anything.
From the tool's definition Search PharmGKB for a pharmacogenomics gene; returns gene ID, location, clinical summary.
Attacks that exploit this kind of access
The rule that runs pharmgkb.pharmacology.gene_search safely
PolicyLayer is an MCP gateway: it sits between your AI agents and Apibase, and checks every tool call against a rule you set before the call runs. Nothing changes on the server itself. For pharmgkb.pharmacology.gene_search, this is the rule to start with:
pharmgkb.pharmacology.gene_search is read-only, so it stays allowed. Everything else on the server is denied unless you say otherwise.
The button opens the PolicyLayer dashboard: create your workspace, connect Apibase, apply this rule, and every pharmgkb.pharmacology.gene_search call is checked against it from then on.
Questions about pharmgkb.pharmacology.gene_search
Search PharmGKB for a pharmacogenomics gene by HGNC symbol (e.g. CYP2C9, CYP2D6, BRCA1, VKORC1, TPMT). Returns the PharmGKB gene ID, chromosomal location (GRCh38), strand, CPIC/AMP gene status, allele type, VIP tier, and plain-text clinical summary. CPIC genes have validated drug-dosing guidelines. AMP genes are on the AMP Tier I/II actionable list. Source: PharmGKB, CC BY-SA 4.0. It is categorised as a Read tool in the Apibase MCP Server, which means it retrieves data without modifying state.
pharmgkb.pharmacology.gene_search accepts 1 parameter: symbol. Required: symbol. The full parameter table on this page comes from the server's own tool schema.
Register the Apibase MCP server in PolicyLayer and add a rule for pharmgkb.pharmacology.gene_search: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches Apibase. Nothing to install.
pharmgkb.pharmacology.gene_search is a Read tool with low risk. Read-only tools are generally safe to allow by default.
Yes. Add a rate_limit block to the pharmgkb.pharmacology.gene_search rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.
Set action: deny in the PolicyLayer policy for pharmgkb.pharmacology.gene_search. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.
pharmgkb.pharmacology.gene_search is provided by the Apibase MCP server (apibase-mcp-client). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.
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