science.ensembl.sequence_region
Retrieve the raw DNA sequence for a genomic region (e.g. "17:7668402-7687550" on GRCh38). Returns the nucleotide sequence, molecule type, and sequence length. Useful for primer design, variant context, and comparative sequence analysis. Data: rest.ensembl.org (EMBL-EBI / Wellcome Sanger Institute...
This record as markdown: /tools/io-github-whiteknightonhorse-apibase/science.ensembl.sequence-region.md
What science.ensembl.sequence_region does on Apibase
AI agents call science.ensembl.sequence_region to retrieve information from Apibase without modifying anything. It is typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.
| Parameter | Type | Required | Description |
|---|---|---|---|
region | string | Yes | Genomic region in "chromosome:start-end" format, GRCh38 coordinates (e.g. "X:1000000-1000100", "17:7668402-7687550" for TP53) |
species | string | Yes | Species name in Ensembl format — scientific snake_case (e.g. "homo_sapiens") or common alias (e.g. "human", "mouse") |
Parameters from the server's own tool schema.
Why science.ensembl.sequence_region is rated Low
Tool retrieves public genomic data with no side effects or modifications. Read-only query operation with minimal misuse risk.
From the tool's definition Retrieve the raw DNA sequence for a genomic region. Returns the nucleotide sequence, molecule type, and sequence length.
Attacks that exploit this kind of access
The rule that runs science.ensembl.sequence_region safely
PolicyLayer is an MCP gateway: it sits between your AI agents and Apibase, and checks every tool call against a rule you set before the call runs. Nothing changes on the server itself. For science.ensembl.sequence_region, this is the rule to start with:
science.ensembl.sequence_region is read-only, so it stays allowed. Everything else on the server is denied unless you say otherwise.
The button opens the PolicyLayer dashboard: create your workspace, connect Apibase, apply this rule, and every science.ensembl.sequence_region call is checked against it from then on.
Questions about science.ensembl.sequence_region
Retrieve the raw DNA sequence for a genomic region (e.g. "17:7668402-7687550" on GRCh38). Returns the nucleotide sequence, molecule type, and sequence length. Useful for primer design, variant context, and comparative sequence analysis. Data: rest.ensembl.org (EMBL-EBI / Wellcome Sanger Institute), no auth required. It is categorised as a Read tool in the Apibase MCP Server, which means it retrieves data without modifying state.
science.ensembl.sequence_region accepts 2 parameters: region, species. Required: region, species. The full parameter table on this page comes from the server's own tool schema.
Register the Apibase MCP server in PolicyLayer and add a rule for science.ensembl.sequence_region: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches Apibase. Nothing to install.
science.ensembl.sequence_region is a Read tool with low risk. Read-only tools are generally safe to allow by default.
Yes. Add a rate_limit block to the science.ensembl.sequence_region rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.
Set action: deny in the PolicyLayer policy for science.ensembl.sequence_region. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.
science.ensembl.sequence_region is provided by the Apibase MCP server (apibase-mcp-client). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.
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