AI agents call search_gene_variants_clinvar to retrieve information from Pgx without modifying anything — typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.
This tool queries ClinVar, a public database of genetic variants and their clinical significance. No description provided, but the naming pattern and server purpose (pharmacogenomics analysis via database connections) clearly indicate data retrieval only. No side effects, no data modification, no code execution, no financial impact. Classified as Read with high confidence based on context and naming convention.
From the tool's definition Tool name 'search_gene_variants_clinvar' indicates querying/searching ClinVar database for variant information.
Attacks that exploit this kind of access
search_gene_variants_clinvar. It is categorised as a Read tool in the Pgx MCP Server, which means it retrieves data without modifying state.
Register the Pgx MCP server in PolicyLayer and add a rule for search_gene_variants_clinvar: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches Pgx. Nothing to install.
search_gene_variants_clinvar is a Read tool with low risk. Read-only tools are generally safe to allow by default.
Yes. Add a rate_limit block to the search_gene_variants_clinvar rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.
Set action: deny in the PolicyLayer policy for search_gene_variants_clinvar. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.
search_gene_variants_clinvar is provided by the Pgx MCP server (julius-schmidt/mcp-pharmacogenomics). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.
Every MCP server has a record like this.
Type a name, get the same breakdown: verified identity, auth posture, risk grade, capabilities, recommended policy.
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