AI agents call get_drug_gene_interactions to retrieve information from Gwas without modifying anything — typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.
This tool queries an external database (PharmGKB) to retrieve pre-existing drug-gene interaction data. It performs a lookup operation with no side effects, does not execute code, does not modify data, and does not commit financial or destructive actions. It is a straightforward read/retrieval operation typical of bioinformatics research queries.
From the tool's definition Tool description states 'Get drug-gene interaction annotations from PharmGKB for a specific gene' - the verb 'get' and the absence of any modification, deletion, or execution language indicates a retrieval operation only.
Attacks that exploit this kind of access
Get drug-gene interaction annotations from PharmGKB for a specific gene. It is categorised as a Read tool in the Gwas MCP Server, which means it retrieves data without modifying state.
Register the Gwas MCP server in PolicyLayer and add a rule for get_drug_gene_interactions: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches Gwas. Nothing to install.
get_drug_gene_interactions is a Read tool with low risk. Read-only tools are generally safe to allow by default.
Yes. Add a rate_limit block to the get_drug_gene_interactions rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.
Set action: deny in the PolicyLayer policy for get_drug_gene_interactions. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.
get_drug_gene_interactions is provided by the Gwas MCP server (muslus/gwas-mcp). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.
Every MCP server has a record like this.
Type a name, get the same breakdown: verified identity, auth posture, risk grade, capabilities, recommended policy.
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