myvariant.variants.info
Retrieve comprehensive annotation for a single genetic variant by its dbSNP rsID (e.g. "rs671") or HGVS genomic notation. Returns complete annotation from 30+ integrated databases: ClinVar clinical significance and disease conditions, CADD pathogenicity scores (raw + PHRED), gnomAD exome and geno...
This record as markdown: /tools/io-github-whiteknightonhorse-apibase/myvariant.variants.info.md
What myvariant.variants.info does on Apibase
AI agents call myvariant.variants.info to retrieve information from Apibase without modifying anything. It is typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.
| Parameter | Type | Required | Description |
|---|---|---|---|
fields | string | — | Comma-separated annotation fields to retrieve. Default: dbsnp,clinvar,cadd,gnomad_exome,gnomad_genome,snpeff,vcf,chrom,hg19. Optional: dbnsfp (functional predic |
variant_id | string | Yes | Variant identifier — dbSNP rsID (e.g. "rs58991260"), or HGVS genomic notation (e.g. "chr7:g.140453134A>T" — use URL-encoded form when needed). rsIDs are preferr |
Parameters from the server's own tool schema.
Why myvariant.variants.info is rated Low
Tool queries genetic variant databases and returns annotations without modifying data.
From the tool's definition Retrieve comprehensive annotation for a single genetic variant
Attacks that exploit this kind of access
The rule that runs myvariant.variants.info safely
PolicyLayer is an MCP gateway: it sits between your AI agents and Apibase, and checks every tool call against a rule you set before the call runs. Nothing changes on the server itself. For myvariant.variants.info, this is the rule to start with:
myvariant.variants.info is read-only, so it stays allowed. Everything else on the server is denied unless you say otherwise.
The button opens the PolicyLayer dashboard: create your workspace, connect Apibase, apply this rule, and every myvariant.variants.info call is checked against it from then on.
Questions about myvariant.variants.info
Retrieve comprehensive annotation for a single genetic variant by its dbSNP rsID (e.g. "rs671") or HGVS genomic notation. Returns complete annotation from 30+ integrated databases: ClinVar clinical significance and disease conditions, CADD pathogenicity scores (raw + PHRED), gnomAD exome and genome allele frequencies across ancestry groups (AFR, EUR, EAS, AMR, ASJ), SnpEff predicted functional consequences with HGVS coding and protein notations, dbSNP allele frequency data, COSMIC somatic mutation records, CIViC clinical interpretations, and genomic coordinates in both GRCh37 (hg19) and GRCh38 (hg38). Essential for variant interpretation pipelines, pharmacogenomics analysis, and clinical variant classification (ACMG guidelines). It is categorised as a Read tool in the Apibase MCP Server, which means it retrieves data without modifying state.
myvariant.variants.info accepts 2 parameters: fields, variant_id. Required: variant_id. The full parameter table on this page comes from the server's own tool schema.
Register the Apibase MCP server in PolicyLayer and add a rule for myvariant.variants.info: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches Apibase. Nothing to install.
myvariant.variants.info is a Read tool with low risk. Read-only tools are generally safe to allow by default.
Yes. Add a rate_limit block to the myvariant.variants.info rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.
Set action: deny in the PolicyLayer policy for myvariant.variants.info. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.
myvariant.variants.info is provided by the Apibase MCP server (apibase-mcp-client). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.
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