get_cids_by_smiles
Obtain the CID corresponding to the drug smiles
This record as markdown: /tools/gentel-lab-origenemcp/get-cids-by-smiles.md
What get_cids_by_smiles does on OrigeneMCP
AI agents call get_cids_by_smiles to retrieve information from OrigeneMCP without modifying anything. It is typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.
Why get_cids_by_smiles is rated Low
The tool retrieves data (CID identifiers) based on input (SMILES notation). It performs a read-only lookup against a biomedical database without creating, modifying, deleting, or executing any code. The blast radius of misuse is minimal—an agent could retrieve incorrect compound identifiers, but this would not alter data, execute code, or cause financial harm.
From the tool's definition Tool name 'get_cids_by_smiles' and description 'Obtain the CID corresponding to the drug smiles' indicate a lookup/retrieval operation that converts a chemical structure representation (SMILES) into a PubChem Compound ID (CID).
Attacks that exploit this kind of access
The rule that runs get_cids_by_smiles safely
PolicyLayer is an MCP gateway: it sits between your AI agents and OrigeneMCP, and checks every tool call against a rule you set before the call runs. Nothing changes on the server itself. For get_cids_by_smiles, this is the rule to start with:
get_cids_by_smiles is read-only, so it stays allowed. Everything else on the server is denied unless you say otherwise.
The button opens the PolicyLayer dashboard: create your workspace, connect OrigeneMCP, apply this rule, and every get_cids_by_smiles call is checked against it from then on.
Questions about get_cids_by_smiles
Obtain the CID corresponding to the drug smiles. It is categorised as a Read tool in the OrigeneMCP MCP Server, which means it retrieves data without modifying state.
Register the Origene MCP server in PolicyLayer and add a rule for get_cids_by_smiles: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches OrigeneMCP. Nothing to install.
get_cids_by_smiles is a Read tool with low risk. Read-only tools are generally safe to allow by default.
Yes. Add a rate_limit block to the get_cids_by_smiles rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.
Set action: deny in the PolicyLayer policy for get_cids_by_smiles. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.
get_cids_by_smiles is provided by the Origene MCP server (gentel-lab/origenemcp). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.
More on Origene, and thousands of servers like it.
This server
Across the catalogue