This record as markdown: /tools/gentel-lab-origenemcp/post-variation.md
What post_variation does on OrigeneMCP
AI agents use post_variation to create or update resources in OrigeneMCP, usually the action step of a workflow, after the agent has gathered context. Every call changes real data in your OrigeneMCP environment.
Why post_variation is rated Medium
The 'post' prefix strongly suggests a Write operation (creates or modifies data). Given the biomedical context of OrigeneMCP (variation databases like ClinVar), this tool likely submits or registers variation data. Without a description, confidence is moderate. It is classified as Write rather than Execute because 'post' implies data creation, not arbitrary command execution.
From the tool's definition Tool name 'post_variation' uses the 'post' verb, which conventionally indicates data creation or submission. The description is empty, preventing definitive assessment of scope and reversibility.
Attacks that exploit this kind of access
The rule that runs post_variation safely
PolicyLayer is an MCP gateway: it sits between your AI agents and OrigeneMCP, and checks every tool call against a rule you set before the call runs. Nothing changes on the server itself. For post_variation, this is the rule to start with:
post_variation stays usable, but capped: an agent stuck in a loop can't make hundreds of changes a minute. Everything else on the server is denied unless you say otherwise.
The button opens the PolicyLayer dashboard: create your workspace, connect OrigeneMCP, apply this rule, and every post_variation call is checked against it from then on.
Questions about post_variation
post_variation is a write tool on the Origene MCP server. It is categorised as a Write tool in the OrigeneMCP MCP Server, which means it can create or modify data. Consider rate limits to prevent runaway writes.
Register the Origene MCP server in PolicyLayer and add a rule for post_variation: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches OrigeneMCP. Nothing to install.
post_variation is a Write tool with medium risk. Write tools should be rate-limited to prevent accidental bulk modifications.
Yes. Add a rate_limit block to the post_variation rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.
Set action: deny in the PolicyLayer policy for post_variation. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.
post_variation is provided by the Origene MCP server (gentel-lab/origenemcp). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.
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