Low Risk

get_variant_liftover

get_variant_liftover

How to control get_variant_liftover ↓

What get_variant_liftover does on gnomAD MCP Server

AI agents call get_variant_liftover to retrieve information from gnomAD MCP Server without modifying anything — typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.

Low Risk

Why get_variant_liftover needs a policy

Liftover in genomics refers to converting genomic coordinates between reference genome builds. The 'get_' prefix combined with the querying nature of the gnomAD API (a read-only database) indicates this tool retrieves coordinate mapping information without modifying data. No write, execution, destructive, or financial capabilities are evident. Confidence is 0.85 rather than higher due to the missing description.

From the tool's definition Tool name 'get_variant_liftover' and context indicate retrieval of liftover information; part of a genomic data query API (gnomAD) alongside other read-only tools like get_variant_info, get_gene_info, and search_for_genes.

Documented attack patterns abuse exactly the kind of access get_variant_liftover gives an agent:

How to control get_variant_liftover

PolicyLayer is an MCP gateway — it sits between your AI agents and gnomAD MCP Server, and nothing reaches the server without passing your rules. This is the rule we recommend for get_variant_liftover:

policy.json
{
  "version": "1",
  "default": "deny",
  "tools": {
    "get_variant_liftover": {}
  }
}

get_variant_liftover is read-only, so it stays allowed — but everything else on the server is denied unless you say otherwise.

  1. Create a free account and register gnomAD MCP Server — nothing to install.
  2. Add this policy — paste it, or build it visually.
  3. Point your MCP client (Claude, Cursor, anything) at your gateway URL.
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Related tools and policies

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Questions about get_variant_liftover

What does the get_variant_liftover tool do? +

get_variant_liftover. It is categorised as a Read tool in the gnomAD MCP Server MCP Server, which means it retrieves data without modifying state.

How do I enforce a policy on get_variant_liftover? +

Register the gnomAD MCP Server MCP server in PolicyLayer and add a rule for get_variant_liftover: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches gnomAD MCP Server. Nothing to install.

What risk level is get_variant_liftover? +

get_variant_liftover is a Read tool with low risk. Read-only tools are generally safe to allow by default.

Can I rate-limit get_variant_liftover? +

Yes. Add a rate_limit block to the get_variant_liftover rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.

How do I block get_variant_liftover completely? +

Set action: deny in the PolicyLayer policy for get_variant_liftover. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.

What MCP server provides get_variant_liftover? +

get_variant_liftover is provided by the gnomAD MCP Server MCP server (koido/gnomad-mcp). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.

Enforce policy on every gnomAD MCP Server tool call.

Start from gnomAD MCP Server, add the rest of your stack, and see everything your agents can call. Then put policy on all of it.

Free to start. No card required.

12 gnomAD MCP Server tools catalogued and risk-classified — across an index of 43,000+ MCP servers.

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