AI agents call annotate_rsid to retrieve information from OpenCRAVAT without modifying anything — typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.
The tool queries and retrieves variant annotation data for a dbSNP rsID. This is a read-only lookup operation consistent with the server's purpose of annotating variants with existing datasets. No data is created, modified, or deleted.
From the tool's definition "Annotate a dbSNP rsID" - retrieves annotation data for a given rsID identifier; no modification or side effects implied
Documented attack patterns abuse exactly the kind of access annotate_rsid gives an agent:
PolicyLayer is an MCP gateway — it sits between your AI agents and OpenCRAVAT, and nothing reaches the server without passing your rules. This is the rule we recommend for annotate_rsid:
{
"version": "1",
"default": "deny",
"tools": {
"annotate_rsid": {}
}
}annotate_rsid is read-only, so it stays allowed — but everything else on the server is denied unless you say otherwise.
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Annotate a dbSNP rsID. It is categorised as a Read tool in the OpenCRAVAT MCP Server, which means it retrieves data without modifying state.
Register the OpenCRAVAT MCP server in PolicyLayer and add a rule for annotate_rsid: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches OpenCRAVAT. Nothing to install.
annotate_rsid is a Read tool with low risk. Read-only tools are generally safe to allow by default.
Yes. Add a rate_limit block to the annotate_rsid rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.
Set action: deny in the PolicyLayer policy for annotate_rsid. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.
annotate_rsid is provided by the OpenCRAVAT MCP server (karchinlab/oc-mcp). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.
Start from OpenCRAVAT, add the rest of your stack, and see everything your agents can call. Then put policy on all of it.
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7 OpenCRAVAT tools catalogued and risk-classified — across an index of 43,000+ MCP servers.