Low Risk

compare_models

Compare multiple NONMEM runs by OFV, delta-OFV, parameter counts, and AIC. Accepts a list of run directories or .ext file paths.

How to control compare_models ↓

What compare_models does on Nonmem

AI agents call compare_models to retrieve information from Nonmem without modifying anything — typically the context-gathering step in research, monitoring, and reporting workflows, before the agent takes action elsewhere.

Low Risk

Why compare_models needs a policy

This tool reads and compares existing NONMEM run results (OFV, delta-OFV, parameter counts, AIC) from run directories or .ext files. It performs no modifications, executions, or deletions — purely analytical/read operation on existing data.

From the tool's definition Compare multiple NONMEM runs by OFV, delta-OFV, parameter counts, and AIC. Accepts a list of run directories or .ext file paths.

Documented attack patterns abuse exactly the kind of access compare_models gives an agent:

How to control compare_models

PolicyLayer is an MCP gateway — it sits between your AI agents and Nonmem, and nothing reaches the server without passing your rules. This is the rule we recommend for compare_models:

policy.json
{
  "version": "1",
  "default": "deny",
  "tools": {
    "compare_models": {}
  }
}

compare_models is read-only, so it stays allowed — but everything else on the server is denied unless you say otherwise.

  1. Create a free account and register Nonmem — nothing to install.
  2. Add this policy — paste it, or build it visually.
  3. Point your MCP client (Claude, Cursor, anything) at your gateway URL.
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Related tools and policies

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Questions about compare_models

What does the compare_models tool do? +

Compare multiple NONMEM runs by OFV, delta-OFV, parameter counts, and AIC. Accepts a list of run directories or .ext file paths. It is categorised as a Read tool in the Nonmem MCP Server, which means it retrieves data without modifying state.

How do I enforce a policy on compare_models? +

Register the Nonmem MCP server in PolicyLayer and add a rule for compare_models: allow, deny, rate-limit, or require approval. Point your MCP client at the PolicyLayer proxy URL and the rule is enforced on every call, before it reaches Nonmem. Nothing to install.

What risk level is compare_models? +

compare_models is a Read tool with low risk. Read-only tools are generally safe to allow by default.

Can I rate-limit compare_models? +

Yes. Add a rate_limit block to the compare_models rule in your PolicyLayer policy. For example, setting max: 10 and window: 60 limits the tool to 10 calls per minute. Rate limits are tracked per agent session and reset automatically.

How do I block compare_models completely? +

Set action: deny in the PolicyLayer policy for compare_models. The AI agent will receive a policy violation error and cannot call the tool. You can also include a reason field to explain why the tool is blocked.

What MCP server provides compare_models? +

compare_models is provided by the Nonmem MCP server (sueinchoi/nonmem-mcp-server). PolicyLayer sits as a proxy in front of this server to enforce policies before tool calls reach the server.

Enforce policy on every Nonmem tool call.

Start from Nonmem, add the rest of your stack, and see everything your agents can call. Then put policy on all of it.

Free to start. No card required.

22 Nonmem tools catalogued and risk-classified — across an index of 43,000+ MCP servers.

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